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trem2  (Santa Cruz Biotechnology)


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    Santa Cruz Biotechnology trem2
    Trem2, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 93/100, based on 69 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/trem2/product/Santa Cruz Biotechnology
    Average 93 stars, based on 69 article reviews
    trem2 - by Bioz Stars, 2026-06
    93/100 stars

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    Enrichment analysis and immune-cell infiltration based on risk groups. (A) GSEA analysis showing top 5 pathways between low- and high-risk groups. (B) Heatmap of differences in pathways between low- and high-risk groups. (C) Stacked bar chart showing infiltration proportions of immune cells using ssGSEA. (D) Correlation analysis of FNDC1, S100A8, and <t>TREM2</t> with differential immune infiltrating cells. (E) Box plot of differences in 7 types of immune cells within the low- and high-risk groups. (F) Correlation analysis between S100A8 and neutrophils. (G) The differences in the scores of dysfunction, exclusion, MSI, and TIDE between low- and high-risk groups. (H) The differences in the expression of immune checkpoint between low- and high-risk groups. Ns, not significant. * indicate p<0.05, ** indicate p<0.01, *** indicate p<0.001, **** indicate p<0.0001.
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    Image Search Results


    Enrichment analysis and immune-cell infiltration based on risk groups. (A) GSEA analysis showing top 5 pathways between low- and high-risk groups. (B) Heatmap of differences in pathways between low- and high-risk groups. (C) Stacked bar chart showing infiltration proportions of immune cells using ssGSEA. (D) Correlation analysis of FNDC1, S100A8, and TREM2 with differential immune infiltrating cells. (E) Box plot of differences in 7 types of immune cells within the low- and high-risk groups. (F) Correlation analysis between S100A8 and neutrophils. (G) The differences in the scores of dysfunction, exclusion, MSI, and TIDE between low- and high-risk groups. (H) The differences in the expression of immune checkpoint between low- and high-risk groups. Ns, not significant. * indicate p<0.05, ** indicate p<0.01, *** indicate p<0.001, **** indicate p<0.0001.

    Journal: Frontiers in Oncology

    Article Title: A novel prognostic signature based on mitochondrial permeability transition-driven necrosis genes for biochemical recurrence prediction in prostate cancer

    doi: 10.3389/fonc.2026.1775602

    Figure Lengend Snippet: Enrichment analysis and immune-cell infiltration based on risk groups. (A) GSEA analysis showing top 5 pathways between low- and high-risk groups. (B) Heatmap of differences in pathways between low- and high-risk groups. (C) Stacked bar chart showing infiltration proportions of immune cells using ssGSEA. (D) Correlation analysis of FNDC1, S100A8, and TREM2 with differential immune infiltrating cells. (E) Box plot of differences in 7 types of immune cells within the low- and high-risk groups. (F) Correlation analysis between S100A8 and neutrophils. (G) The differences in the scores of dysfunction, exclusion, MSI, and TIDE between low- and high-risk groups. (H) The differences in the expression of immune checkpoint between low- and high-risk groups. Ns, not significant. * indicate p<0.05, ** indicate p<0.01, *** indicate p<0.001, **** indicate p<0.0001.

    Article Snippet: The following were the antibody concentrations for western blotting: rabbit polyclonal anti-FNDC1 antibody (1:1000, catalog no. bs-8460R; Bioss, Beijing, China), rabbit polyclonal anti-TREM2 antibody (1:1000, catalog no. HY- P80920 ; MedChemExpress, Monmouth Junction, NJ, USA), and rabbit polyclonal anti-S100A8 antibody (1:1000, catalog no. AF7929; Beyotime, Shanghai, China), and mouse monoclonal anti-GAPDH (1:2000, 60004-1-Ig, Proteintech, China).

    Techniques: Expressing

    Validation of FNDC1, S100A8, and TREM2 expression. (A) The mRNA expression levels of FNDC1, S100A8, and TREM2 in TCGA-PRAD cohort. (B) The mRNA expression levels of FNDC1, S100A8 and TREM2 were confirmed by q-PCR between paratumor(PT) and prostate cancer tissue. (C, D) The protein expression levels of FNDC1, S100A8 and TREM2 were confirmed by western blot between paratumor(PT) and prostate cancer tissue(T). (E) Immunohistochemistry micrographs revealing FNDC1, S100A8 and TREM2 expression between paratumor(PT) and prostate cancer tissue(T). **P< 0.01; ***P< 0.001.

    Journal: Frontiers in Oncology

    Article Title: A novel prognostic signature based on mitochondrial permeability transition-driven necrosis genes for biochemical recurrence prediction in prostate cancer

    doi: 10.3389/fonc.2026.1775602

    Figure Lengend Snippet: Validation of FNDC1, S100A8, and TREM2 expression. (A) The mRNA expression levels of FNDC1, S100A8, and TREM2 in TCGA-PRAD cohort. (B) The mRNA expression levels of FNDC1, S100A8 and TREM2 were confirmed by q-PCR between paratumor(PT) and prostate cancer tissue. (C, D) The protein expression levels of FNDC1, S100A8 and TREM2 were confirmed by western blot between paratumor(PT) and prostate cancer tissue(T). (E) Immunohistochemistry micrographs revealing FNDC1, S100A8 and TREM2 expression between paratumor(PT) and prostate cancer tissue(T). **P< 0.01; ***P< 0.001.

    Article Snippet: The following were the antibody concentrations for western blotting: rabbit polyclonal anti-FNDC1 antibody (1:1000, catalog no. bs-8460R; Bioss, Beijing, China), rabbit polyclonal anti-TREM2 antibody (1:1000, catalog no. HY- P80920 ; MedChemExpress, Monmouth Junction, NJ, USA), and rabbit polyclonal anti-S100A8 antibody (1:1000, catalog no. AF7929; Beyotime, Shanghai, China), and mouse monoclonal anti-GAPDH (1:2000, 60004-1-Ig, Proteintech, China).

    Techniques: Biomarker Discovery, Expressing, Western Blot, Immunohistochemistry